Title page Ligand signature in the membrane dynamics of single TrkA receptor molecules
نویسندگان
چکیده
Ligand signature in the membrane dynamics of single TrkA receptor molecules L. Marchetti , A. Callegari , S. Luin, G. Signore, A. Viegi, F. Beltram and A. Cattaneo 1 NEST, Scuola Normale Superiore and Istituto Nanoscienze – CNR, Piazza San Silvestro 12, I56126 Pisa, Italy. 2 BioSNS Laboratory, Scuola Normale Superiore, c/o Istituto di Neuroscienze del CNR, via Moruzzi 1, I-56100 Pisa, Italy. 3 IIT@NEST, Center for Nanotechnology Innovation, Piazza San Silvestro 12, I-56126 Pisa, Italy.
منابع مشابه
Ligand signature in the membrane dynamics of single TrkA receptor molecules.
The neurotrophin receptor TrkA (also known as NTRK1) is known to be crucially involved in several physio-pathological processes. However, a clear description of the early steps of ligand-induced TrkA responses at the cell plasma membrane is missing. We have exploited single particle tracking and TIRF microscopy to study TrkA membrane lateral mobility and changes of oligomerization state upon bi...
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